Microsponge Technology for Innovative Drug Delivery System
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Microsponge Drug Delivery System Using Indomethacin
In the present study controlled release formulation of Indomethacin microsponges were prepared by using Eudragit RS 100, pH independent release retardant polymer and PVA, stabilizer or emulsifier. Microsponges were prepared by Quasi emulsion solvent diffusion method by changing drug polymer ratio (3:1, 4:1, 5:1) and process was optimized. Microsponges were evaluated by micromeritic properties, ...
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In pharmaceutical industry, various controlled released dosage forms like solid formulation, semi solid formulation and topical preparation have more importance due to efficacy and patient compliance. Topical preparations have some disadvantages like unpleasant odour, greasiness and skin irritation and fail to reach the systemic circulation in sufficient amounts in few cases. This problem is ov...
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Microsponge were prepared by liquid-liquid suspension polymerization of styrene and methyl methacrylate. Microsponges were dispersed in gel prepared by using carbopol 940 and evaluated for drug release using Franz diffusion cell. Free flowing powder with size distribution 30 to 107 μm was obtained. The average drug release from the gels containing microspongic fluconazole was 67.81% in 12 h. dr...
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Several plant extracts and phytoconstituents, despite having excellent bioactivity in vitro, demonstrate less or no in vivo actions due to their poor lipid solubility or improper molecular size or destruction in gut. Drug delivery system for polyphenolic phytoconstituents (phytosomes) was prepared by complexing polyphenolic phytoconstituents with phospholipid mainly phosphatidylcholine wh...
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The oral route is most popular route for the administration of therapeutic agents because of the low cost of therapy and ease of administration lead to high levels of patient compliance. The most popular oral solid dosage forms are tablets and capsules. Many patients find it difficult to swallow tablets and hard gelatin capsules particularly pediatric and geriatric patients and do not take thei...
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ژورنال
عنوان ژورنال: International Journal of Scientific Research in Science and Technology
سال: 2020
ISSN: 2395-602X,2395-6011
DOI: 10.32628/ijsrst207521